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Global variability in gene expression and alternative splicing is modulated by mitochondrial content

Noise in gene expression is a main determinant of phenotypic variability. Increasing experimental evidence suggests that genome-wide cellular constraints largely contribute to the heterogeneity observed in gene products. It is still unclear, however, which global factors affect gene expression noise...

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Détails bibliographiques
Publié dans:Genome Res
Auteurs principaux: Guantes, Raul, Rastrojo, Alberto, Neves, Ricardo, Lima, Ana, Aguado, Begoña, Iborra, Francisco J.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417112/
https://ncbi.nlm.nih.gov/pubmed/25800673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.178426.114
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