Moderate Alcohol Drinking and the Amygdala Proteome: Identification and Validation of Calcium/Calmodulin Dependent Kinase II and AMPA Receptor Activity as Novel Molecular Mechanisms of the Positive Reinforcing Effects of Alcohol

BACKGROUND: Despite worldwide consumption of moderate amounts of alcohol, the neural mechanisms that mediate the transition from use to abuse are not fully understood. METHODS: Here, we conducted a high-through put screen of the amygdala proteome in mice after moderate alcohol drinking (n = 12/group...

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Publicado no:Biol Psychiatry
Main Authors: Salling, Michael C., Faccidomo, Sara P., Li, Chia, Psilos, Kelly, Galunas, Christina, Spanos, Marina, Agoglia, Abigail E., Kash, Thomas L., Hodge, Clyde W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417085/
https://ncbi.nlm.nih.gov/pubmed/25579851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2014.10.020
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