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Regulatory Role of Collagen V in Establishing Mechanical Properties of Tendons and Ligaments is Tissue-Dependent

Patients with classic (type I) Ehlers-Danlos Syndrome (EDS), characterized by heterozygous mutations in the Col5a1 and Col5a2 genes, exhibit connective tissue hyperelasticity and recurrent joint dislocations, indicating a potential regulatory role for collagen V in joint stabilizing soft tissues. Th...

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Bibliografske podrobnosti
izdano v:J Orthop Res
Main Authors: Connizzo, Brianne K., Freedman, Benjamin R., Fried, Joanna H., Sun, Mei, Birk, David E., Soslowsky, Louis J.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417070/
https://ncbi.nlm.nih.gov/pubmed/25876927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.22893
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