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Improving the predictive value of interventional animal models data

For many chronic diseases, translational success using the animal model paradigm has reached an impasse. Using Alzheimer’s disease as an example, this review employs a networks-based method to assess repeatability of outcomes across species, by intervention and mechanism. Over 75% of animal studies...

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Bibliografische gegevens
Gepubliceerd in:Drug Discov Today
Hoofdauteur: Zeiss, Caroline J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417064/
https://ncbi.nlm.nih.gov/pubmed/25448761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2014.10.015
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