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Improving the predictive value of interventional animal models data

For many chronic diseases, translational success using the animal model paradigm has reached an impasse. Using Alzheimer’s disease as an example, this review employs a networks-based method to assess repeatability of outcomes across species, by intervention and mechanism. Over 75% of animal studies...

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Detalles Bibliográficos
Publicado en:Drug Discov Today
Autor Principal: Zeiss, Caroline J.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417064/
https://ncbi.nlm.nih.gov/pubmed/25448761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2014.10.015
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