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Improving the predictive value of interventional animal models data
For many chronic diseases, translational success using the animal model paradigm has reached an impasse. Using Alzheimer’s disease as an example, this review employs a networks-based method to assess repeatability of outcomes across species, by intervention and mechanism. Over 75% of animal studies...
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| Published in: | Drug Discov Today |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4417064/ https://ncbi.nlm.nih.gov/pubmed/25448761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2014.10.015 |
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