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Synthesis and Characterization of Gadolinium - Peptidomimetic Complex as an α(v)β(3) Integrin Targeted MR Contrast Agent

There is growing interest in small and rigid peptidomimetic α(v)β(3) integrin antagonists that are readily synthesized and characterized and amenable to physiological conditions. Peptidomimetic 4-[2-(3,4,5,6-tetrahydropyrimidine-2-ylamino)ethyloxy]benzoyl-2-[N-(3-amino-neopenta-1-carbamyl)]-aminoeth...

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Détails bibliographiques
Publié dans:Bioorg Med Chem Lett
Auteurs principaux: Kim, Young-Seung, Zhou, Yang, Bryant, Henry, Milenic, Diane E., Baidoo, Kwamena E., Lewis, Bobbi K., Frank, Joseph A., Brechbiel, Martin W.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417025/
https://ncbi.nlm.nih.gov/pubmed/25870133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.03.092
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