A hyphal-specific chitin synthase gene (CHS2) is not essential for growth, dimorphism, or virulence of Candida albicans.

In the dimorphic fungus Candida albicans, the CHS2 gene encodes a chitin synthase that is expressed preferentially in the hyphal form. Gene disruption of CHS2 in this diploid asexual fungus was achieved by the "ura-blaster" protocol described for Saccharomyces [Alani, E., Cao, L. & Kleckner, N. (198...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Gow, N A, Robbins, P W, Lester, J W, Brown, A J, Fonzi, W A, Chapman, T, Kinsman, O S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44169/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8016141/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.13.6216
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