P. falciparum and P. vivax Epitope-Focused VLPs Elicit Sterile Immunity to Blood Stage Infections

In order to design P. falciparum preerythrocytic vaccine candidates, a library of circumsporozoite (CS) T and B cell epitopes displayed on the woodchuck hepatitis virus core antigen (WHcAg) VLP platform was produced. To test the protective efficacy of the WHcAg-CS VLPs, hybrid CS P. berghei/P. falci...

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Vydáno v:PLoS One
Hlavní autoři: Whitacre, David C., Espinosa, Diego A., Peters, Cory J., Jones, Joyce E., Tucker, Amy E., Peterson, Darrell L., Zavala, Fidel P., Milich, David R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416889/
https://ncbi.nlm.nih.gov/pubmed/25933001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124856
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