Increasing Adipocyte Lipoprotein Lipase Improves Glucose Metabolism in High Fat Diet-induced Obesity

Lipid accumulation in liver and skeletal muscle contributes to co-morbidities associated with diabetes and obesity. We made a transgenic mouse in which the adiponectin (Adipoq) promoter drives expression of lipoprotein lipase (LPL) in adipocytes to potentially increase adipose tissue lipid storage....

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Walton, R. Grace, Zhu, Beibei, Unal, Resat, Spencer, Michael, Sunkara, Manjula, Morris, Andrew J., Charnigo, Richard, Katz, Wendy S., Daugherty, Alan, Howatt, Deborah A., Kern, Philip A., Finlin, Brian S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416858/
https://ncbi.nlm.nih.gov/pubmed/25784555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.628487
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