Plasma Free Hemoglobin and Microcirculatory Response to Fresh or Old Blood Transfusions in Sepsis

BACKGROUND: Free hemoglobin (fHb) may induce vasoconstriction by scavenging nitric oxide. It may increase in older blood units due to storage lesions. This study evaluated whether old red blood cell transfusion increases plasma fHb in sepsis and how the microvascular response may be affected. METHOD...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Damiani, Elisa, Adrario, Erica, Luchetti, Michele Maria, Scorcella, Claudia, Carsetti, Andrea, Mininno, Nicoletta, Pierantozzi, Silvia, Principi, Tiziana, Strovegli, Daniele, Bencivenga, Rosella, Gabrielli, Armando, Romano, Rocco, Pelaia, Paolo, Ince, Can, Donati, Abele
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416810/
https://ncbi.nlm.nih.gov/pubmed/25932999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122655
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