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Acidosis Mediates the Switching of G(s)-PKA and G(i)-PKC(ε) Dependence in Prolonged Hyperalgesia Induced by Inflammation
Chronic inflammatory pain, when not effectively treated, is a costly health problem and has a harmful effect on all aspects of health-related quality of life. Previous studies suggested that in male Sprague Dawley rats, prostaglandin E(2) (PGE(2))-induced short-term hyperalgesia depends on protein k...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4416776/ https://ncbi.nlm.nih.gov/pubmed/25933021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125022 |
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