Prognostic Impact of Reduced Connexin43 Expression and Gap Junction Coupling of Neoplastic Stromal Cells in Giant Cell Tumor of Bone

Missense mutations of the GJA1 gene encoding the gap junction channel protein connexin43 (Cx43) cause bone malformations resulting in oculodentodigital dysplasia (ODDD), while GJA1 null and ODDD mutant mice develop osteopenia. In this study we investigated Cx43 expression and channel functions in gi...

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Publicat a:PLoS One
Autors principals: Balla, Peter, Maros, Mate Elod, Barna, Gabor, Antal, Imre, Papp, Gergo, Sapi, Zoltan, Athanasou, Nicholas Anthony, Benassi, Maria Serena, Picci, Pierro, Krenacs, Tibor
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416750/
https://ncbi.nlm.nih.gov/pubmed/25933380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125316
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