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A Weighted Polygenic Risk Score Using 14 Known Susceptibility Variants to Estimate Risk and Age Onset of Psoriasis in Han Chinese

With numbers of common variants identified mainly through genome-wide association studies (GWASs), there is great interest in incorporating the findings into screening individuals at high risk of psoriasis. The purpose of this study is to establish genetic prediction models and evaluate its discrimi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yin, Xianyong, Cheng, Hui, Lin, Yan, Wineinger, Nathan E., Zhou, Fusheng, Sheng, Yujun, Yang, Chao, Li, Pan, Li, Feng, Shen, Changbing, Yang, Sen, Schork, Nicholas J., Zhang, Xuejun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416725/
https://ncbi.nlm.nih.gov/pubmed/25933357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125369
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