Endothelin-1 but not Angiotensin II Contributes to Functional Aging in Murine Carotid Arteries

AIMS: Aging is a major risk factor for carotid artery disease and stroke. Endothelin-1 (ET-1) and angiotensin II (Ang II) are important modifiers of vascular disease, partly through increased activity of NADPH oxidase and vasoconstrictor prostanoids. Since the renin-angiotensin and endothelin system...

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Udgivet i:Life Sci
Main Authors: Meyer, Matthias R., Fredette, Natalie C., Barton, Matthias, Prossnitz, Eric R.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416653/
https://ncbi.nlm.nih.gov/pubmed/24607776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2014.02.027
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