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Altered excitatory and inhibitory inputs to striatal medium-sized spiny neurons and cortical pyramidal neurons in the Q175 mouse model of Huntington's disease

The Q175 knockin mouse model of Huntington's disease (HD) carries a CAG trinucleotide expansion of the human mutant huntingtin allele in its native mouse genomic context and recapitulates the genotype more closely than transgenic models. In this study we examined the progression of changes in i...

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Pubblicato in:J Neurophysiol
Autori principali: Indersmitten, Tim, Tran, Conny H., Cepeda, Carlos, Levine, Michael S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416625/
https://ncbi.nlm.nih.gov/pubmed/25673747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.01056.2014
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