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Hippocampal glutamate-glutamine (Glx) in adults with Down syndrome: a preliminary study using in vivo proton magnetic resonance spectroscopy ((1)H MRS)

BACKGROUND: Down syndrome (DS), or trisomy 21, is one of the most common autosomal mutations. People with DS have intellectual disability (ID) and are at significantly increased risk of developing Alzheimer’s disease (AD). The biological associates of both ID and AD in DS are poorly understood, but...

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Bibliografiske detaljer
Udgivet i:J Neurodev Disord
Main Authors: Tan, Giles MY, Beacher, Felix, Daly, Eileen, Horder, Jamie, Prasher, Verinder, Hanney, Maria-Luisa, Morris, Robin, Lovestone, Simon, Murphy, Kieran C, Simmons, Andrew, Murphy, Declan GM
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416419/
https://ncbi.nlm.nih.gov/pubmed/25937842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1866-1955-6-42
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