Hippocampal glutamate-glutamine (Glx) in adults with Down syndrome: a preliminary study using in vivo proton magnetic resonance spectroscopy ((1)H MRS)

BACKGROUND: Down syndrome (DS), or trisomy 21, is one of the most common autosomal mutations. People with DS have intellectual disability (ID) and are at significantly increased risk of developing Alzheimer’s disease (AD). The biological associates of both ID and AD in DS are poorly understood, but...

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Detalhes bibliográficos
Publicado no:J Neurodev Disord
Main Authors: Tan, Giles MY, Beacher, Felix, Daly, Eileen, Horder, Jamie, Prasher, Verinder, Hanney, Maria-Luisa, Morris, Robin, Lovestone, Simon, Murphy, Kieran C, Simmons, Andrew, Murphy, Declan GM
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416419/
https://ncbi.nlm.nih.gov/pubmed/25937842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1866-1955-6-42
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