Plasma and urine metabolic profiles are reflective of altered beta-oxidation in non-diabetic obese subjects and patients with type 2 diabetes mellitus

OBJECTIVES: The two primary pathophysiological characteristics of patients with type 2 diabetes mellitus (T2DM) are insulin resistance (IR) and beta cell dysfunction. It has been proposed that the development of IR is secondary to the accumulation of triacylglycerols and fatty acids in the muscle an...

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Published in:Diabetol Metab Syndr
Main Authors: Villarreal-Pérez, Jesús Zacarías, Villarreal-Martínez, Jesús Zacarías, Lavalle-González, Fernando Javier, Torres-Sepúlveda, María del Rosario, Ruiz-Herrera, Consuelo, Cerda-Flores, Ricardo Martín, Castillo-García, Erik Rubén, Rodríguez-Sánchez, Irám Pablo, Martínez de Villarreal, Laura Elia
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416397/
https://ncbi.nlm.nih.gov/pubmed/25937838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-5996-6-129
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