Long-range regulatory interactions at the 4q25 atrial fibrillation risk locus involve PITX2c and ENPEP

BACKGROUND: Recent genome-wide association studies have uncovered genomic loci that underlie an increased risk for atrial fibrillation, the major cardiac arrhythmia in humans. The most significant locus is located in a gene desert at 4q25, approximately 170 kilobases upstream of PITX2, which codes f...

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Bibliographic Details
Published in:BMC Biol
Main Authors: Aguirre, Luis A, Alonso, M Eva, Badía-Careaga, Claudio, Rollán, Isabel, Arias, Cristina, Fernández-Miñán, Ana, López-Jiménez, Elena, Aránega, Amelia, Gómez-Skarmeta, José Luis, Franco, Diego, Manzanares, Miguel
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416339/
https://ncbi.nlm.nih.gov/pubmed/25888893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-015-0138-0
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