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An experimental study of the effect of pre-operative administration of cilostazol on random skin flap survival in rats: double blinded randomized controlled trial

BACKGROUND: Insufficient arterial blood flow is the one cause of flap necrosis. Cilostazol is an inhibitor of phosphodiesterase III and increases cyclic AMP level in vascular smooth muscle cell causing vasodilation. Therefore, effect of cilostazol is expected to improve the viability of the flap. ME...

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Detalhes bibliográficos
Publicado no:Ann Surg Innov Res
Main Authors: Burusapat, Chairat, Paengnoi, Janjira, Satayasoontorn, Kantang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416283/
https://ncbi.nlm.nih.gov/pubmed/25937828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13022-015-0011-4
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