Preimplantation single-cell analysis of multiple genetic loci by whole-genome amplification.

Due to the limited amount of DNA in a single diploid cell, preimplantation genetic diagnosis has relied on single- or dual-locus analyses in biopsied blastomers. We have applied single-cell whole-genome preamplification to PCR-based analysis of multiple disease loci from the same diploid cell. This...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Snabes, M C, Chong, S S, Subramanian, S B, Kristjansson, K, DiSepio, D, Hughes, M R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44162/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7517043/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.13.6181
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