The Nitric Oxide Donor Pentaerythritol Tetranitrate Reduces Platelet Activation in Congestive Heart Failure

BACKGROUND: Platelet activation associated with endothelial dysfunction and impaired endogenous platelet inhibition is part of the cardiovascular phenotype of congestive heart failure (CHF) and contributes to the increased risk for thromboembolic complications. Pentaerythritol tetranitrate (PETN) ha...

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Bibliographic Details
Published in:PLoS One
Main Authors: Flierl, Ulrike, Fraccarollo, Daniela, Widder, Julian D., Micka, Jan, Neuser, Jonas, Bauersachs, Johann, Schäfer, Andreas
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415973/
https://ncbi.nlm.nih.gov/pubmed/25928879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123621
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