Identification of a Comprehensive Spectrum of Genetic Factors for Hereditary Breast Cancer in a Chinese Population by Next-Generation Sequencing

The genetic etiology of hereditary breast cancer has not been fully elucidated. Although germline mutations of high-penetrance genes such as BRCA1/2 are implicated in development of hereditary breast cancers, at least half of all breast cancer families are not linked to these genes. To identify a co...

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Publicado en:PLoS One
Autores principales: Yang, Xiaochen, Wu, Jiong, Lu, Jingsong, Liu, Guangyu, Di, Genhong, Chen, Canming, Hou, Yifeng, Sun, Menghong, Yang, Wentao, Xu, Xiaojing, Zhao, Ying, Hu, Xin, Li, Daqiang, Cao, Zhigang, Zhou, Xiaoyan, Huang, Xiaoyan, Liu, Zhebin, Chen, Huan, Gu, Yanzi, Chi, Yayun, Yan, Xia, Han, Qixia, Shen, Zhenzhou, Shao, Zhimin, Hu, Zhen
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415911/
https://ncbi.nlm.nih.gov/pubmed/25927356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125571
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