Modeling and study of the mechanism of dilated cardiomyopathy using induced pluripotent stem cells derived from individuals with Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is caused by mutations in the dystrophin gene (DMD), and is characterized by progressive weakness in skeletal and cardiac muscles. Currently, dilated cardiomyopathy due to cardiac muscle loss is one of the major causes of lethality in late-stage DMD patients. To stu...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Principais autores: Lin, Bo, Li, Yang, Han, Lu, Kaplan, Aaron D., Ao, Ying, Kalra, Spandan, Bett, Glenna C. L., Rasmusson, Randall L., Denning, Chris, Yang, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415895/
https://ncbi.nlm.nih.gov/pubmed/25791035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.019505
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