Effect of netazepide, a gastrin/CCK(2) receptor antagonist, on gastric acid secretion and rabeprazoleinduced hypergastrinaemia in healthy subjects

AIMS: To compare gastric acid suppression by netazepide, a gastrin/CCK(2) receptor antagonist, with that by a proton pump inhibitor (PPI), and to determine if netazepide can prevent the trophic effects of PPI-induced hypergastrinaemia. METHODS: Thirty healthy subjects completed a double-blind, rando...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Boyce, Malcolm, Dowen, Sally, Turnbull, Gillian, van den Berg, Frans, Zhao, Chun-Mei, Chen, Duan, Black, James
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Clinical Trials
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415711/
https://ncbi.nlm.nih.gov/pubmed/25335860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12534
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