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Drug-induced regulatory overcompensation has motivational consequences: Implications for homeostatic and allostatic models of drug addiction

Initial administration of 60% nitrous oxide (N(2)O) at 21°C ambient temperature reduces core temperature (Tc) in rats, but tolerance develops to this hypothermic effect over several administrations. After additional N(2)O administrations, a hyperthermic overcompensation (sign-reversal) develops such...

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Detalhes bibliográficos
Publicado no:Temperature (Austin)
Main Authors: Ramsay, Douglas S, Woods, Stephen C, Kaiyala, Karl J
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415621/
https://ncbi.nlm.nih.gov/pubmed/25938126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23328940.2014.944802
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