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Effect of HDAC Inhibitors on Corneal Keratocyte Mechanical Phenotypes in 3-D Collagen Matrices

PURPOSE: Histone deacetylase inhibitors (HDAC) have been shown to inhibit the TGFβ-induced myofibroblast transformation of corneal fibroblasts in 2-D culture. However, the effect of HDAC inhibitors on keratocyte spreading, contraction, and matrix remodeling in 3-D culture has not been directly asses...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Vis
मुख्य लेखकों: Koppaka, Vindhya, Lakshman, Neema, Petroll, W. Matthew
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Molecular Vision 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415596/
https://ncbi.nlm.nih.gov/pubmed/25999677
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