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Normobaric hyperoxia slows BBB damage and expands the therapeutic time window for tPA treatment in cerebral ischemia

BACKGROUND AND PURPOSE: Prolonged ischemia causes blood-brain barrier (BBB) damage and increases the incidence of neurovasculature complications secondary to reperfusion. Therefore, targeting ischemic BBB damage pathogenesis is critical to reducing neurovasculature complications and expanding the th...

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Detalhes bibliográficos
Publicado no:Stroke
Main Authors: Liang, Jia, Qi, Zhifeng, Liu, Wenlan, Wang, Peng, Shi, Wenjuan, Dong, Wen, Ji, Xunming, Luo, Yumin, Liu, Ke Jian
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414814/
https://ncbi.nlm.nih.gov/pubmed/25804925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.114.008599
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