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Normobaric hyperoxia slows BBB damage and expands the therapeutic time window for tPA treatment in cerebral ischemia
BACKGROUND AND PURPOSE: Prolonged ischemia causes blood-brain barrier (BBB) damage and increases the incidence of neurovasculature complications secondary to reperfusion. Therefore, targeting ischemic BBB damage pathogenesis is critical to reducing neurovasculature complications and expanding the th...
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Publicado no: | Stroke |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4414814/ https://ncbi.nlm.nih.gov/pubmed/25804925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.114.008599 |
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