Synergistic binding of the leader and core peptides by the lantibiotic synthetase HalM2

Lanthipeptides are a class of ribosomally-produced and post-translationally modified peptides (RiPPs) that possess a variety of biological activities, but typically act as antimicrobial agents (lantibiotics). Haloduracin is a lantibiotic that is composed of two post-translationally modified peptides...

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Bibliographic Details
Published in:ACS Chem Biol
Main Authors: Thibodeaux, Gabrielle N., McClerren, Amanda L., Ma, Yunli, Gancayco, Marc R., van der Donk, Wilfred A.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414810/
https://ncbi.nlm.nih.gov/pubmed/25619528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb5009876
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