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HIF targets in bone remodeling and metastatic disease

The bone marrow isa hypoxic microenvironment that is rich in growth factors and blood vessels and is readily colonized by tumor cells disseminated from numerous cancers including tumors of the breast, prostate, lung, and skin. The origin of metastatic growth promoting factors for tumor cells dissemi...

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Foilsithe in:Pharmacol Ther
Main Authors: Johnson, Rachelle W., Schipani, Ernestina, Giaccia, Amato J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414805/
https://ncbi.nlm.nih.gov/pubmed/25681658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2015.02.002
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