Normalization of raised sodium absorption and raised calcium-mediated chloride secretion by adenovirus-mediated expression of cystic fibrosis transmembrane conductance regulator in primary human cystic fibrosis airway epithelial cells.

Cystic fibrosis airway epithelia exhibit a spectrum of ion transport properties that differ from normal, including not only defective cAMP-mediated Cl- secretion, but also increased Na+ absorption and increased Ca(2+)-mediated Cl- secretion. In the present study, we examined whether adenovirus-media...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Johnson, L G, Boyles, S E, Wilson, J, Boucher, R C
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC441478/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7533790/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117789
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