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Aldehyde dehydrogenase homologous folate enzymes: evolutionary switch between cytoplasmic and mitochondrial localization

Cytosolic and mitochondrial 10-formyltetrahydrofolate dehydrogenases are products of separate genes in vertebrates but only one such gene is present in invertebrates. There is a significant degree of sequence similarity between the two enzymes due to an apparent origin of the gene for the mitochondr...

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Bibliographische Detailangaben
Veröffentlicht in:Chem Biol Interact
Hauptverfasser: Krupenko, Natalia I., Holmes, Roger S., Tsybovsky, Yaroslav, Krupenko, Sergey A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414694/
https://ncbi.nlm.nih.gov/pubmed/25549576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2014.12.022
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