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A Novel Angiotensin Type I Receptor Antagonist, Fimasartan, Prevents Doxorubicin-induced Cardiotoxicity in Rats

Angiotensin receptor blockers (ARBs) have organ-protective effects in heart failure and may be also effective in doxorubicin-induced cardiomyopathy (DOX-CMP); however, the efficacy of ARBs on the prevention of DOX-CMP have not been investigated. We performed a preclinical experiment to evaluate the...

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Détails bibliographiques
Publié dans:J Korean Med Sci
Auteurs principaux: Chang, Sung-A, Lim, Byung-Kwan, Lee, You Jung, Hong, Mi-Kyung, Choi, Jin-Oh, Jeon, Eun-Seok
Format: Artigo
Langue:Inglês
Publié: The Korean Academy of Medical Sciences 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414639/
https://ncbi.nlm.nih.gov/pubmed/25931786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2015.30.5.559
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