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The Xenopus laevis Atg4B Protease: Insights into Substrate Recognition and Application for Tag Removal from Proteins Expressed in Pro- and Eukaryotic Hosts

During autophagy, members of the ubiquitin-like Atg8 protein family get conjugated to phosphatidylethanolamine and act as protein-recruiting scaffolds on the autophagosomal membrane. The Atg4 protease produces mature Atg8 from C-terminally extended precursors and deconjugates lipid-bound Atg8. We no...

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Publicat a:PLoS One
Autors principals: Frey, Steffen, Görlich, Dirk
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414272/
https://ncbi.nlm.nih.gov/pubmed/25923686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125099
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