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Repeated nitrous oxide exposure in rats causes a thermoregulatory sign-reversal with concurrent activation of opposing thermoregulatory effectors

Initial administration of 60% nitrous oxide (N(2)O) to rats at an ambient temperature of 21°C decreases core temperature (Tc), primarily via increased heat loss (HL). Over repeated N(2)O administrations, rats first develop tolerance to this hypothermia and subsequently exhibit hyperthermia (a sign-r...

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Detalhes bibliográficos
Publicado no:Temperature (Austin)
Main Authors: Ramsay, Douglas S, Woods, Stephen C, Kaiyala, Karl J
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414259/
https://ncbi.nlm.nih.gov/pubmed/25938127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23328940.2014.944809
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