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Glycolytic metabolism influences global chromatin structure

Metabolic rewiring, specifically elevated glycolytic metabolism is a hallmark of cancer. Global chromatin structure regulates gene expression, DNA repair, and also affects cancer progression. But the interrelationship between tumor metabolism and chromatin architecture remain unclear. Here we show t...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Xue-Song, Little, John B., Yuan, Zhi-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414184/
https://ncbi.nlm.nih.gov/pubmed/25784656
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