RASSF10 suppresses colorectal cancer growth by activating P53 signaling and sensitizes colorectal cancer cell to docetaxel

RASSF10 has previously been reported to be frequently methylated in a number of malignancies. To understand the importance of RASSF10 inactivation in colorectal carcinogenesis, eight colorectal cancer cell lines, 89 cases of primary colorectal cancer and 5 cases of normal colorectal mucosa were exam...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Guo, Jing, Yang, Yage, Yang, Yunsheng, Linghu, Enqiang, Zhan, Qimin, Brock, Malcolm V., Herman, James G., Zhang, Bingyong, Guo, Mingzhou
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414183/
https://ncbi.nlm.nih.gov/pubmed/25638156
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