Oncoprotein mdig contributes to silica-induced pulmonary fibrosis by altering balance between Th17 and Treg T cells

Mineral dust-induced gene (mdig, also named Mina53) was first identified from alveolar macrophages of the coal miners with chronic lung inflammation or fibrosis, but how this gene is involved in lung diseases is poorly understood. Here we show that heterozygotic knockout of mdig (mdig+/−) ameliorate...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Thakur, Chitra, Wolfarth, Michael, Sun, Jiaying, Zhang, Yadong, Lu, Yongju, Battelli, Lori, Porter, Dale W., Chen, Fei
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414149/
https://ncbi.nlm.nih.gov/pubmed/25669985
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