Trafficking protein particle complex 6A delta (TRAPPC6AΔ) is an extracellular plaque-forming protein in the brain

Tumor suppressor WWOX is involved in the progression of cancer and neurodegeneration. Here, we examined whether protein aggregation occurs in the brain of nondemented, middle-aged humans and whether this is associated with WWOX downregulation. We isolated an N-terminal internal deletion isoform, TPC...

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I publikationen:Oncotarget
Huvudupphovsmän: Chang, Jean-Yun, Lee, Ming-Hui, Lin, Sing-Ru, Yang, Li-Yi, Sun, H. Sunny, Sze, Chun-I, Hong, Qunying, Lin, Yee-Shin, Chou, Ying-Tsen, Hsu, Li-Jin, Jan, Ming-Shiou, Gong, Cheng-Xin, Chang, Nan-Shan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2015
Ämnen:
Gerotarget (Focus on Aging): Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414138/
https://ncbi.nlm.nih.gov/pubmed/25650666
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