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Defining novel parameters for the optimal priming and expansion of minor histocompatibility antigen-specific T cells in culture
BACKGROUND: Adoptive transfer of minor histocompatibility antigen (MiHA)-specific T cells is a promising therapy for patients with hematological cancers. However, the efficacy of the transferred cells is hampered by the acquisition of terminal effector differentiation and exhaustion features during...
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| Veröffentlicht in: | J Transl Med |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4413989/ https://ncbi.nlm.nih.gov/pubmed/25925868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0495-z |
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