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Functional Genetic Targeting of Embryonic Kidney Progenitor Cells Ex Vivo

The embryonic mammalian metanephric mesenchyme (MM) is a unique tissue because it is competent to generate the nephrons in response to Wnt signaling. An ex vivo culture in which the MM is separated from the ureteric bud (UB), the natural inducer, can be used as a classic tubule induction model for s...

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Détails bibliographiques
Publié dans:J Am Soc Nephrol
Auteurs principaux: Junttila, Sanna, Saarela, Ulla, Halt, Kimmo, Manninen, Aki, Pärssinen, Heikki, Lecca, M. Rita, Brändli, André W., Sims-Lucas, Sunder, Skovorodkin, Ilya, Vainio, Seppo J.
Format: Artigo
Langue:Inglês
Publié: American Society of Nephrology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413750/
https://ncbi.nlm.nih.gov/pubmed/25201883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013060584
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