Low Circulating Levels of IGF-1 in Healthy Adults Are Associated With Reduced β-Cell Function, Increased Intramyocellular Lipid, and Enhanced Fat Utilization During Fasting

CONTEXT: Low serum IGF-1 levels have been linked to increased risk for development of type 2 diabetes. However, the physiological role of IGF-1 in glucose metabolism is not well characterized. OBJECTIVE: Our objective was to explore glucose and lipid metabolism associated with variations in serum IG...

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Bibliografiske detaljer
Udgivet i:J Clin Endocrinol Metab
Main Authors: Thankamony, Ajay, Capalbo, Donatella, Marcovecchio, M. Loredana, Sleigh, Alison, Jørgensen, Sine Wanda, Hill, Nathan R., Mooslehner, Katrin, Yeo, Giles S. H., Bluck, Les, Juul, Anders, Vaag, Allan, Dunger, David B.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413372/
https://ncbi.nlm.nih.gov/pubmed/24617714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-4542
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