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Rgg protein structure–function and inhibition by cyclic peptide compounds

Peptide pheromone cell–cell signaling (quorum sensing) regulates the expression of diverse developmental phenotypes (including virulence) in Firmicutes, which includes common human pathogens, e.g., Streptococcus pyogenes and Streptococcus pneumoniae. Cytoplasmic transcription factors known as “Rgg p...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Parashar, Vijay, Aggarwal, Chaitanya, Federle, Michael J., Neiditch, Matthew B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413276/
https://ncbi.nlm.nih.gov/pubmed/25847993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1500357112
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