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Activation of the Silent Secondary Metabolite Production by Introducing Neomycin-Resistance in a Marine-Derived Penicillium purpurogenum G59

Introduction of neomycin-resistance into a marine-derived, wild-type Penicillium purpurogenum G59 resulted in activation of silent biosynthetic pathways for the secondary metabolite production. Upon treatment of G59 spores with neomycin and dimethyl sulfoxide (DMSO), a total of 56 mutants were obtai...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mar Drugs
Prif Awduron: Wu, Chang-Jing, Yi, Le, Cui, Cheng-Bin, Li, Chang-Wei, Wang, Nan, Han, Xiao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413221/
https://ncbi.nlm.nih.gov/pubmed/25913704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md13042465
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