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Hydrolysis and transesterification of platelet-activating factor by lecithin-cholesterol acyltransferase.

Purified lecithin-cholesterol acyltransferase (LCAT, EC 2.3.1.43) from human plasma was found to hydrolyze platelet-activating factor (PAF) to lyso-PAF and acetate. In addition, it catalyzed the transfer of the acetate group from PAF to lysophosphatidylcholine, forming lyso-PAF and a 1-acyl analog o...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Liu, M, Subbaiah, P V
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1994
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44132/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8016111/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.13.6035
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