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Shikonin causes cell-cycle arrest and induces apoptosis by regulating the EGFR–NF-κB signalling pathway in human epidermoid carcinoma A431 cells
Shikonin, a naphthoquinone pigment isolated from the Chinese herbal Zicao, has been shown to exhibit antioxidant and anticancer effects. In the present study, we investigated the antiproliferative and pro-apoptotic effects of shikonin on A431 cells and explored the underlying molecular mechanisms. I...
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Gepubliceerd in: | Biosci Rep |
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Hoofdauteurs: | , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Portland Press Ltd.
2015
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4413019/ https://ncbi.nlm.nih.gov/pubmed/25720435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20150002 |
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