Intracellular FGF14 (iFGF14) Is Required for Spontaneous and Evoked Firing in Cerebellar Purkinje Neurons and for Motor Coordination and Balance

Mutations in FGF14, which encodes intracellular fibroblast growth factor 14 (iFGF14), have been linked to spinocerebellar ataxia (SCA27). In addition, mice lacking Fgf14 (Fgf14(−/−)) exhibit an ataxia phenotype resembling SCA27, accompanied by marked changes in the excitability of cerebellar granule...

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Argitaratua izan da:J Neurosci
Egile Nagusiak: Bosch, Marie K., Carrasquillo, Yarimar, Ransdell, Joseph L., Kanakamedala, Ajay, Ornitz, David M., Nerbonne, Jeanne M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2015
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Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412895/
https://ncbi.nlm.nih.gov/pubmed/25926453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2663-14.2015
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