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Mechanisms of maladaptive repair after AKI leading to accelerated kidney ageing and CKD

Acute kidney injury is an increasingly common complication of hospital admission and is associated with high levels of morbidity and mortality. A hypotensive, septic, or toxic insult can initiate a cascade of events, resulting in impaired microcirculation, activation of inflammatory pathways and tub...

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Pubblicato in:Nat Rev Nephrol
Autori principali: Ferenbach, David A., Bonventre, Joseph V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412815/
https://ncbi.nlm.nih.gov/pubmed/25643664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneph.2015.3
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