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Involvement of the H1 histamine receptor, p38 MAP kinase, MLCK, and Rho/ROCK in histamine-induced endothelial barrier dysfunction
OBJECTIVE: The mechanisms by which histamine increases microvascular permeability remain poorly understood. We tested the hypothesis that H1 receptor activation disrupts the endothelial barrier and investigated potential downstream signals. METHODS: We used confluent endothelial cell (EC) monolayers...
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| Publicado no: | Microcirculation |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4412777/ https://ncbi.nlm.nih.gov/pubmed/25582918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/micc.12189 |
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