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Effects of disrupting medial prefrontal cortex GABA transmission on decision-making in a rodent gambling task

RATIONALE: Decision-making is a complex cognitive process that is mediated, in part, by subregions of the medial prefrontal cortex (PFC). Decision-making is impaired in a number of psychiatric conditions including schizophrenia. Notably, people with schizophrenia exhibit reductions in GABA function...

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Pubblicato in:Psychopharmacology (Berl)
Autori principali: Paine, TA, O’Hara, A, Plaut, B, Lowes, DC
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412766/
https://ncbi.nlm.nih.gov/pubmed/25420610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-014-3816-7
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